Validation of surface-to-volume ratio measurements derived from oscillating gradient spin echo on a clinical scanner using anisotropic fiber phantoms.

@article{Lemberskiy2017ValidationOS,
  title={Validation of surface-to-volume ratio measurements derived from oscillating gradient spin echo on a clinical scanner using anisotropic fiber phantoms.},
  author={Gregory Lemberskiy and Steven H. Baete and Martijn A. Cloos and Dmitry S. Novikov and Els Fieremans},
  journal={NMR in biomedicine},
  year={2017},
  volume={30 5}
}
A diffusion measurement in the short-time surface-to-volume ratio (S/V) limit (Mitra et al., Phys Rev Lett. 1992;68:3555) can disentangle the free diffusion coefficient from geometric restrictions to diffusion. Biophysical parameters, such as the S/V of tissue membranes, can be used to estimate microscopic length scales non-invasively. However, due to gradient strength limitations on clinical MRI scanners, pulsed gradient spin echo (PGSE) measurements are impractical for probing the S/V limit… CONTINUE READING
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Time‐dependent diffusion coefficient as a probe of geometry

  • PN Sen
  • Concepts Magn Reson A
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