Validation of primary and secondary outcomes and classification of mode of death among patients with clinical evidence of heart failure after a myocardial infarction: a report from the Acute Infarction Ramipril Efficacy (AIRE) Study Investigators.

@article{Cleland1993ValidationOP,
  title={Validation of primary and secondary outcomes and classification of mode of death among patients with clinical evidence of heart failure after a myocardial infarction: a report from the Acute Infarction Ramipril Efficacy (AIRE) Study Investigators.},
  author={John Gf Cleland and Leif Rw Erhardt and Alistair Scott Hall and Christian Winter and Stephen G. Ball},
  journal={Journal of cardiovascular pharmacology},
  year={1993},
  volume={22 Suppl 9},
  pages={S22-7}
}
The AIRE study--a trial involving over 2,000 patients with clinical heart failure after myocardial infarction--assessed different outcomes. The primary outcome was total mortality. The secondary outcome was time to death, or progression to severe/resistant heart failure, reinfarction or stroke. Tertiary analyses included hospitalization and mode of death. To obtain maximum quality in the validation of outcomes and to optimize the quality of the data in the study, an end-points committee… CONTINUE READING

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