Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer

@inproceedings{Larsson2011ValidationOP,
  title={Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer},
  author={Anna H. Larsson and Marie Fridberg and Alexander Gaber and Bj{\"o}rn Nodin and Per Lev{\'e}en and G{\"o}ran B. J{\"o}nsson and Mathias Uhl{\'e}n and Helgi Birgisson and Karin Jirstr{\"o}m},
  booktitle={BMC Cancer},
  year={2011}
}
Podocalyxin-like 1 (PODXL) is a cell-adhesion glycoprotein and stem cell marker that has been associated with an aggressive tumour phenotype and adverse outcome in several cancer types. We recently demonstrated that overexpression of PODXL is an independent factor of poor prognosis in colorectal cancer (CRC). The aim of this study was to validate these results in two additional independent patient cohorts and to examine the correlation between PODXL mRNA and protein levels in a subset of… CONTINUE READING
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