Validation of immunoassays for bioanalysis: a pharmaceutical industry perspective.

@article{Findlay2000ValidationOI,
  title={Validation of immunoassays for bioanalysis: a pharmaceutical industry perspective.},
  author={John W. A. Findlay and Wendell Carl Smith and Jean Wenqing. Lee and Gerald D. Nordblom and Ira Das and Binodh S. DeSilva and M. D. Faseeulla Khan and Ronald R Bowsher},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={2000},
  volume={21 6},
  pages={
          1249-73
        }
}
Immunoassays are bioanalytical methods in which quantitation of the analyte depends on the reaction of an antigen (analyte) and an antibody. Although applicable to the analysis of both low molecular weight xenobiotic and macromolecular drugs, these procedures currently find most consistent application in the pharmaceutical industry to the quantitation of protein molecules. Immunoassays are also frequently applied in such important areas as the quantitation of biomarker molecules which indicate… CONTINUE READING
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