Validation of high-performance liquid chromatography-boron-doped diamond detection for assessing hepatic glutathione redox status.

@article{Park2010ValidationOH,
  title={Validation of high-performance liquid chromatography-boron-doped diamond detection for assessing hepatic glutathione redox status.},
  author={Hea Jin Park and Eunice Mah and Richard S Bruno},
  journal={Analytical biochemistry},
  year={2010},
  volume={407 2},
  pages={151-9}
}
Glutathione redox status is a commonly used oxidative stress biomarker. High-performance liquid chromatography-ultraviolet (HPLC-UV) and HPLC-electrochemical detection (HPLC-ECD) have been used to assess glutathione status but have potential limitations due to challenging sample preparation procedures or electrochemical signal degradation. Thus, this study… CONTINUE READING