Validation of genetically matched wild-type strain and lysyl oxidase-like 1 knockout mouse model of pelvic organ prolapse.

Abstract

OBJECTIVES Lysyl oxidase-like 1 knockout (Loxl1) mice demonstrate deficient elastin homeostasis associated with pelvic organ prolapse (POP). To further investigate the pathophysiology of POP in these animals, a genetically matched homozygous positive (Loxl1) or wild-type strain is needed. This study sought to create and validate genetically matched Loxl1… (More)
DOI: 10.1097/SPV.0000000000000104

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Cite this paper

@article{Couri2014ValidationOG, title={Validation of genetically matched wild-type strain and lysyl oxidase-like 1 knockout mouse model of pelvic organ prolapse.}, author={Bruna M Couri and Ali Borazjani and Andrew T. Lenis and Brian M. Balog and Mei Kuang and Dan Lin and Margot S. Damaser}, journal={Female pelvic medicine & reconstructive surgery}, year={2014}, volume={20 5}, pages={287-92} }