Validation of fluorescence polarization assay (FPA) and comparison with other tests used for diagnosis of B. melitensis infection in sheep.

@article{Minas2005ValidationOF,
  title={Validation of fluorescence polarization assay (FPA) and comparison with other tests used for diagnosis of B. melitensis infection in sheep.},
  author={Anastasios Minas and Athanasia Stournara and Mark Minas and Anastasios Papaioannou and V. Krikelis and Stavros Tselepidis},
  journal={Veterinary microbiology},
  year={2005},
  volume={111 3-4},
  pages={
          211-21
        }
}
Fluorescence polarization assay (FPA) is a new test for the serological diagnosis of Brucella spp. infection in animals. The FPA is validated for the diagnosis of B. melitensis infection in sheep. For this purpose, 166 sera originated from natural infected sheep (verified by culture) and 851 sera originated from healthy animals (reared in areas where B. melitensis was never been isolated) were tested. The optimum cut-off value that offers the highest diagnostic sensitivity (DSn) and diagnostic… CONTINUE READING

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