Validation of an enzyme immunoassay for serodiagnosis of acute Q fever

  title={Validation of an enzyme immunoassay for serodiagnosis of acute Q fever},
  author={David M. Waag and Jeffrey David Chulay and Thomas Marrie and Michael England and Jessie Williams},
  journal={European Journal of Clinical Microbiology and Infectious Diseases},
An enzyme immunoassay was validated for the serodiagnosis of acute Q fever. Minimum positive tests were determined for both serial dilutions and a single dilution of patient sera. To establish the specificity of the test, 152 serum samples were tested from individuals with no evidence of pastCoxiella burnetii infection. Diagnostic titers were set at ≥128 for the IgM and IgG responses to phase I, at ≥512 for the IgM response to phase II and at ≥1,024 for the IgG response to phase IICoxiella… CONTINUE READING

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Acute Q fever

  • T JMarrie
  • Marde TJ (ed): Q fever: the disease
  • 1990
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