Validation of amyloid-beta peptides in CSF diagnosis of neurodegenerative dementias.

@article{Bibl2007ValidationOA,
  title={Validation of amyloid-beta peptides in CSF diagnosis of neurodegenerative dementias.},
  author={Mirko Bibl and Brit Mollenhauer and Piotr Lewczuk and Hermann Esselmann and Stefanie Wolf and Claudia Trenkwalder and Markus Otto and Gerthild Stiens and Eckart Ruether and Johannes Kornhuber and Jens Wiltfang},
  journal={Molecular psychiatry},
  year={2007},
  volume={12 7},
  pages={
          671-80
        }
}
Biomarkers for differential diagnosis of the three most frequent degenerative forms of dementia, Alzheimer's disease (AD), dementia with Lewy bodies (DLB) and frontotemporal dementias (FTD), are currently under intensive investigation, but disease-specific biomarkers for FTD and DLB are still lacking. We analyzed 303 cerebrospinal fluid (CSF) samples of 71 AD, 32 DLB and 36 FTD patients in comparison to 93 various other dementias (OD), 20 peripheral neurologic disease (PND) controls, 25… CONTINUE READING

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