• Corpus ID: 33092636

Validation of a spectrophotometric assay method for bisoprolol using picric acid.

@article{Panainte2013ValidationOA,
  title={Validation of a spectrophotometric assay method for bisoprolol using picric acid.},
  author={Alina Diana Panainte and Nela Bibire and Gladiola Ț{\^a}ntaru and Mihai Apostu and Mădălina Vieriu},
  journal={Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi},
  year={2013},
  volume={117 2},
  pages={
          520-4
        }
}
UNLABELLED Bisoprolol is a drug belonging to beta blockers drugs used primarily for the treatment of cardiovascular diseases. AIM A spectrophotometric method for quantitative determination of bisoprolol was developed based on the formation of a complex combination between bisoprolol and picric acid. MATERIAL AND METHODS The complex combination of bisoprolol and picric acid has a maximum absorbance peak at 420 nm. Optimum working conditions were established and the method was validated… 
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ANALYSIS OF APPROACHES TO THE DEVELOPMENT AND VALIDATION OF THE METHODS OF ANALYSIS OF BISOPROLOL IN DRUGS AND BIOLOGICAL LIQUIDS
  • L. Logoyda
  • Chemistry
    Medical and Clinical Chemistry
  • 2019
TLDR
It is shown that HPLC is the most suitable method for analyses of bisoprolol in substances, drugs, biological liquids to perform routine analysis of medicines, pharmacokinetic (bioequivalence in vivo), dissolution test for final dosages forms.
Utility of picric acid and 2,4 dinitrophenol as chromogenic reagents for visible spectrophotometric quantification of alogliptin

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