Validation of a simple model for predicting liver fibrosis in HIV/hepatitis C virus-coinfected patients.

@article{AlMohri2005ValidationOA,
  title={Validation of a simple model for predicting liver fibrosis in HIV/hepatitis C virus-coinfected patients.},
  author={H. A. Al-Mohri and Curtis N. Cooper and Tanya Murphy and Marina B Klein},
  journal={HIV medicine},
  year={2005},
  volume={6 6},
  pages={375-8}
}
OBJECTIVES Recently, several models incorporating laboratory measurements have been validated for use as surrogate markers for liver fibrosis in hepatitis C virus (HCV) mono-infection, the simplest of these being the aspartate aminotransferase (AST) to platelet ratio index (APRI). We evaluated how well the APRI predicts significant hepatic fibrosis in patients with HIV/HCV coinfection. METHODS Forty-six HIV/HCV-coinfected patients who underwent liver biopsy and had concomitant laboratory… CONTINUE READING

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