Validation of a noninvasive method to measure brain temperature in vivo using 1H NMR spectroscopy.

@article{Corbett1995ValidationOA,
  title={Validation of a noninvasive method to measure brain temperature in vivo using 1H NMR spectroscopy.},
  author={Ronald J. T. Corbett and Abbot R. Laptook and Greg Tollefsbol and B Kim},
  journal={Journal of neurochemistry},
  year={1995},
  volume={64 3},
  pages={1224-30}
}
The goal of this study was to evaluate the potential of using the difference between the 1H NMR frequencies of water and N-acetylaspartic acid (NAA) to measure brain temperature noninvasively. All water-suppressed and non-water-suppressed 1H NMR spectra were obtained at a field strength of 4.7 T using a surface coil. Experiments performed on model solutions revealed a decrease in the difference between NMR frequencies for NAA and water as a linear function of increasing temperature from 14 to… CONTINUE READING

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