Validation of a liquid chromatography-tandem mass spectrometry method for quantification of glycopyrrolate in horse plasma.

@article{Rumpler2011ValidationOA,
  title={Validation of a liquid chromatography-tandem mass spectrometry method for quantification of glycopyrrolate in horse plasma.},
  author={Marc J Rumpler and Richard A. Sams and Patrick T. Colahan},
  journal={Journal of analytical toxicology},
  year={2011},
  volume={35 9},
  pages={656-64}
}
A rapid, sensitive, and specific ultra-high-performance liquid chromatography with heated electrospray ionization-tandem mass spectrometry (UHPLC-HESI-MS-MS) method to detect and quantify glycopyrrolate in horse plasma has been developed and validated. We also determined glycopyrrolate in plasma after oral and intravenous administration of clinically relevant doses to Thoroughbred horses. Calibration was accomplished by weighted, linear regression analysis using a deuterated analogue of… CONTINUE READING

References

Publications referenced by this paper.

Similar Papers

Loading similar papers…