Validation of a Doppler Guide Wire for Intravascular Measurement of Coronary Artery Flow Velocity

@article{Doucette1992ValidationOA,
  title={Validation of a Doppler Guide Wire for Intravascular Measurement of Coronary Artery Flow Velocity},
  author={Joseph W. Doucette and Paul Douglas Corl and H. M. Payne and Arthur E. Flynn and Masami Goto and Menahem Nassi and Jerome Segal},
  journal={Circulation},
  year={1992},
  volume={85},
  pages={1899–1911}
}
BackgroundAn improved intravascular ultrasonic Doppler device could aid the clinical assessment of coronary hemodynamics. We evaluated a new device consisting of a 12-MHz piezoelectric transducer integrated onto the tip of a 0.018-in. flexible, steerable angioplasty guide wire. Methods and ResultsDoppler spectra were recorded in model tubes with pulsatile blood flow and in-line electromagnetic flowmeter. In four straight tubes (i.d., 0.79–4.76 mm), the time average of spectral peak velocity… Expand
Impact of Doppler guidewire size and flow rates on intravascular velocity profiles.
Coronary blood flow velocity measurements by conventional intravascular catheter-based Doppler devices are well known to be affected by catheter size. Moreover, it is of clinical importance that theExpand
Validation of volumetric flow measurements by means of a Doppler-tipped coronary angioplasty guide wire.
TLDR
An in vitro model used to validate volumetric flow measurements obtained with an 0.018-inch angioplasty guidewire with a 12 MHz transducer mounted on its tip suggests that the Doppler spectral output of this device might be accurately applied to estimates of voluetric flow in human coronary arteries. Expand
Use of a Doppler guide wire for intravascular blood flow measurements: a validation study for potential neurologic endovascular applications.
TLDR
The excellent correlation between average peak velocity and volumetric blood flow over a wide range of blood flow conditions and the additional qualitative information of the Doppler guide wire spectra establish a foundation for clinical implementation. Expand
Measurement of volumetric coronary blood flow with a Doppler catheter: validation in an animal model.
TLDR
FFT analysis of the Doppler signal with determination of peak velocity gives the most accurate representation of flow, whereas measurements based on ZCD mean velocities may significantly underestimate coronary flow. Expand
Turbulent flow as a cause for underestimating coronary flow reserve measured by Doppler guide wire
TLDR
Doppler guide wires are a valid tool for exact measurement of coronary flow velocity below a critical Reynolds number of 500 and cardiologists should consider this phenomena in at least 20 % of patients when measuring CFVR for clinical decision making. Expand
Influence of Doppler-tipped guidewire position in coronary artery on blood flow velocity
A pulsatile blood flow model was used to estimate the influence of position of Doppler guide wires with 12 MHz forward looking ultrasound transducers on the average spectral peak velocity. ThreeExpand
Volumetric evaluation of blood flow in normal renal arteries with a Doppler flow wire: a feasibility study.
TLDR
This study demonstrates that direct intravascular determination of RA blood flow with a Doppler-tipped wire is both feasible and relatively uncomplicated, and indicates that blood flow can vary significantly, both in kidneys within the same individual and from person to person. Expand
Position control of intravascular Doppler guidewire: concept of a tracking indicator and its clinical implications.
TLDR
DGW positioning can be optimized using the correlation between APV and M1/M0 as a reference, and for any given APV value, there is a corresponding expected value for M1 /M0 under the condition of optimal positioning. Expand
In vitro validation of volumetric blood flow measurement using Doppler flow wire.
TLDR
Direct volumetric blood flow measurement from received Doppler power using a Doppling wire system is feasible and may potentially be of great clinical value because it allows an accurate assessment of coronary flow and flow reserve with a commercially available flow wire system. Expand
Measurement of volumetric coronary blood flow by simultaneous intravascular two-dimensional and Doppler ultrasound: validation in an animal model.
TLDR
It is concluded that simultaneous 2D and Doppler ultrasound yields accurate estimates of volumetric coronary blood flow (CBF), and an excellent correlation was found between 2D/Doppler-derived and TTU CBF with both constants. Expand
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