Validation of International Society of Urological Pathology (ISUP) grading for prostatic adenocarcinoma in thin core biopsies using TROG 03.04 'RADAR' trial clinical data.

@article{Delahunt2015ValidationOI,
  title={Validation of International Society of Urological Pathology (ISUP) grading for prostatic adenocarcinoma in thin core biopsies using TROG 03.04 'RADAR' trial clinical data.},
  author={Brett Delahunt and Lars Egevad and John R. Srigley and Allison Steigler and Judy D Murray and Christopher Atkinson and Jayne Matthews and Gillian Duchesne and Nigel A Spry and David Christie and David Joseph and John Attia and James Denham},
  journal={Pathology},
  year={2015},
  volume={47 6},
  pages={520-5}
}
In 2014 a consensus conference convened by the International Society of Urological Pathology (ISUP) adopted amendments to the criteria for Gleason grading and scoring (GS) for prostatic adenocarcinoma. The meeting defined a modified grading system based on 5 grading categories (grade 1, GS 3+3; grade 2, GS 3+4; grade 3, GS 4+3; grade 4, GS 8; grade 5, GS 9-10). In this study we have evaluated the prognostic significance of ISUP grading in 496 patients enrolled in the TROG 03.04 RADAR Trial… CONTINUE READING