Validation of Allelic Discrimination Assays for Drug Metabolism

  • Published 2017

Abstract

REFERENCES In the rs762551 locus (CYP1A2), the presence of the AA genotype is indicative of a fast caffeine metabolizer. Genotypes AC are carriers, and genotypes CC are slow metabolizers. In the rs1057910 locus (CYP2C9), the presence of the AA genotype indicates a normal metabolizer of warfarin. Genotypes AC are carriers with a 40% reduction in metabolism… (More)

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