Validation of 24-hour flucytosine MIC determination by comparison with 48-hour determination by the Clinical and Laboratory Standards Institute M27-A3 broth microdilution reference method.

@article{Lockhart2011ValidationO2,
  title={Validation of 24-hour flucytosine MIC determination by comparison with 48-hour determination by the Clinical and Laboratory Standards Institute M27-A3 broth microdilution reference method.},
  author={Shawn R. Lockhart and Carol B Bolden and Naureen Iqbal and Randall J. Kuykendall},
  journal={Journal of clinical microbiology},
  year={2011},
  volume={49 12},
  pages={4322-5}
}
Flucytosine and itraconazole are the only antifungal agents for which the Clinical Laboratory and Standards Institute recommendations include MIC breakpoint readings at 48 h only. Here we show good essential and categorical agreement between the flucytosine MIC readings at 48 and 24 h for Candida species.