Validation and calibration of DEXA body composition in mice.

@article{Brommage2003ValidationAC,
  title={Validation and calibration of DEXA body composition in mice.},
  author={Robert Brommage},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2003},
  volume={285 3},
  pages={E454-9}
}
  • Robert Brommage
  • Published 2003 in
    American journal of physiology. Endocrinology and…
Validated methods of determining murine body composition are required for studies of obesity in mice. Dual-energy X-ray absorptiometry (DEXA) provides a noninvasive approach to assess body fat and lean tissue contents. Similar to DEXA analyses in other species, body fat measurements in mice show acceptable precision but suffer from poor accuracy. Because fat and lean tissues each contain various components, these inaccuracies likely result from selection of inappropriate calibration standards… CONTINUE READING

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