Validated LC-MS / MS Method for the Determination of Rosuvastatin in Human Plasma : Application to a Bioequivalence Study in Chinese Volunteers

@inproceedings{Zhang2011ValidatedL,
  title={Validated LC-MS / MS Method for the Determination of Rosuvastatin in Human Plasma : Application to a Bioequivalence Study in Chinese Volunteers},
  author={Dujuan Zhang and Jing Zhang and Xiaoyan Liu and Chunmin Wei and Rui Zhang and Haojing Song and Han Yao and Guiyan Yuan and Benjie Wang and Ruichen Guo},
  year={2011}
}
A sensitive and selective liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the determination of rosuvastatin in human plasma using gliclazide as an internal standard (IS). Rosuvastatin and gliclazide in plasma were extracted with ethyl acetate, separated on a C18 reversed phase column, eluted with mobile phase of acetonitrile-methanoic acid (0.1%) (60:40, v/v), ionized by positive ion pneumatically assisted electrospray and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 13 references

Similar Papers

Loading similar papers…