• Chemistry
  • Published 2007

Validated Absorption Factor Spectrophotometric and Reversed-Phase High-Performance Liquid Chromatographic Methods for the Determination of Ramipril and Olmesartan Medoxomil in Pharmaceutical Formulations

@inproceedings{Patel2007ValidatedAF,
  title={Validated Absorption Factor Spectrophotometric and Reversed-Phase High-Performance Liquid Chromatographic Methods for the Determination of Ramipril and Olmesartan Medoxomil in Pharmaceutical Formulations},
  author={Chintan Patel and Amit P. Khandhar and Anandi D. Captain and Kalpesh Patel},
  year={2007}
}
Two simple and sensitive spectrophotometric and liquid chromatographic (LC) methods are described for the determination of ramipril and olmesartan medoxomil. The first method was based on the absorption factor. Ramipril and olmesartan medoxomil exhibit λ max at 210 nm and 256 nm respectively. Olmesartan medoxomil has some interference at 210nm, while ramipril do not show any absorption at 256 nm.Quantitative estimation of ramipril was carried out by subtracting the absorption due to olmesartan… CONTINUE READING

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