Vagus nerve stimulation for the treatment of medically intractable seizures. Results of a 1-year open-extension trial. Vagus Nerve Stimulation Study Group.

@article{Salinsky1996VagusNS,
  title={Vagus nerve stimulation for the treatment of medically intractable seizures. Results of a 1-year open-extension trial. Vagus Nerve Stimulation Study Group.},
  author={Martin C. Salinsky and Basim M. Uthman and Ruzica K Ristanovic and Joachim Wernicke and W Brent Tarver},
  journal={Archives of neurology},
  year={1996},
  volume={53 11},
  pages={1176-80}
}
BACKGROUND Chronic vagus nerve stimulation (VNS) continues to be evaluated as an adjunctive treatment for medically intractable seizures. A previous randomized controlled trial of 114 patients demonstrated a significant decrease in seizure frequency during 3 months of VNS at effective stimulation levels. OBJECTIVE To evaluate the efficacy of 1 year of VNS therapy for the treatment of medically refractory partial seizures and the relationship between initial and long-term response. PATIENTS… CONTINUE READING