89 Citations
Evaluating vagus nerve stimulation treatment with heart rate monitoring in pediatric patients with intractable epilepsy
- Medicine, PsychologyChild's Nervous System
- 2021
This study supports the clinical safety and utility of auto-stimulation-enabled VNS models, specifically the SenTiva™ 1000, in treating pediatric patients with intractable epilepsy of various subtypes and etiologies.
Research progress of vagus nerve stimulation in the treatment of epilepsy
- Medicine, PsychologyCNS neuroscience & therapeutics
- 2019
Vagus nerve stimulation (VNS) is one of the neuromodulation methods clinically, which have been approved by the Food and Drug Administration (FDA) and future research directions of VNS for epilepsy are described.
Vagus nerve stimulation for super-refractory status epilepticus in febrile infection–related epilepsy syndrome: a pediatric case report and literature review
- MedicineChild's Nervous System
- 2021
A 29-month-old case is presented, diagnosed with FIRES, whose seizures were successfully controlled by utilization of VNS after ineffective response to intensive pharmacotherapy and ketogenic diet treatment.
Neuromodulation in drug‐resistant epilepsy: A review of current knowledge
- Medicine, PsychologyActa neurologica Scandinavica
- 2022
Although promising outcomes in adults and children with DRE have been achieved, challenges such as heterogeneity among epilepsy types and etiologies, optimization of stimulation parameters, a lack of biomarkers to predict response to neuromodulation therapies, high‐level evidence to aid decision‐making, and direct comparisons between neurommodulatory approaches remain remain.
Therapeutic effects of children with refractory epilepsy after vagus nerve stimulation in Taiwan.
- MedicinePediatrics and neonatology
- 2020
Epilepsy duration as an independent predictor of response to vagus nerve stimulation
- Medicine, PsychologyEpilepsy Research
- 2020
Learnings from 30 years of reported efficacy and safety of vagus nerve stimulation (VNS) for epilepsy treatment: A critical review
- Medicine, PsychologySeizure
- 2020
Vagus Nerve Stimulation Therapy for the Treatment of Seizures in Refractory Postencephalitic Epilepsy: A Retrospective Study
- MedicineFrontiers in Neuroscience
- 2021
This study shows that VNS can reduce the frequency and severity of seizure in patients with refractory PEE and has a good application prospect in patientswith refractary PEE.
Health Technology Assessment Report on Vagus Nerve Stimulation in Drug-Resistant Epilepsy
- Medicine, Political ScienceInternational journal of environmental research and public health
- 2020
Assessment of the clinical, organizational, financial, and economic impact of VNS therapy in drug-resistant epilepsies and the congruity between costs incurred and health service reimbursement indicates VNS as an effective treatment with a potential positive impact on social aspects and on quality of life.
Saudi Arabian Consensus Statement on Vagus Nerve Stimulation for Refractory Epilepsy
- MedicineSaudi journal of medicine & medical sciences
- 2021
A task force was established to create a national consensus on the use of VNS in Saudi Arabia, and evidence is reported as three stages: preimplantation and patient selection, a perioperative phase involving all stakeholders and post-operative care with specific programming pathways.
References
SHOWING 1-10 OF 112 REFERENCES
Reassessment: Vagus nerve stimulation for epilepsy
- Medicine, PsychologyNeurology
- 1999
A July 1997 assessment of the American Academy of Neurology Therapeutics and Technology Subcommittee review of vagus nerve stimulation for epilepsy concluded that it was promising, but not yet established, and a second multicenter, randomized, controlled clinical trial has shown safety and efficacy of VNS for treatment of intractable partial seizures.
Vagal nerve stimulation in children.
- Medicine, PsychologySeminars in pediatric neurology
- 2000
Initial data from open-label, uncontrolled studies suggest that VNS does have some efficacy and safety for those children with refractory epilepsy who have not responded to appropriate trials of antiepileptic drugs.
Vagal nerve stimulation for refractory epilepsy in children: indications and experience at The Hospital for Sick Children
- Medicine, PsychologyChild's Nervous System
- 2006
The results show that VNS implantation can be a safe and effective alternative therapy for children with drug-resistant epilepsy who are not candidates for epilepsy surgery.
Vagus nerve stimulation for treatment of epilepsy in Rett syndrome.
- MedicineDevelopmental medicine and child neurology
- 2006
Quality of life outcomes of note among these patients included reports at 12 months of increased alertness among all seven patients, and VNS was safe and well tolerated, with no surgical complications and no patients requiring explantation of the device.
Vagus nerve stimulation for epilepsy: a meta-analysis of efficacy and predictors of response.
- Medicine, PsychologyJournal of neurosurgery
- 2011
In conclusion, VNS is an effective and relatively safe adjunctive therapy in patients with medically refractory epilepsy not amenable to resection, but it is important to recognize that complete seizure freedom is rarely achieved using VNS and that a quarter of patients do not receive any benefit from therapy.
Vagus nerve stimulation therapy, epilepsy, and device parameters: Scientific basis and recommendations for use
- MedicineNeurology
- 2002
The efficacy of stimulation parameters used in the VNS clinical trials are discussed and an algorithm for the adjustment of VNS device settings is provided.
Vagus nerve stimulation (VNS) is effective in treating catastrophic 1 epilepsy in very young children
- Medicine, PsychologyNeurosurgical Review
- 2008
If resective surgery is inappropriate or refused, VNS can be considered as a well-tolerated and effective procedure even in toddlers affected by severe epilepsy and multiple developmental disabilities.
Vagus Nerve Stimulation for Treatment of Partial Seizures: 2. Safety, Side Effects, and Tolerability
- Medicine
- 1994
Vagus nerve stimulation (VNS) significantly reduces the frequency of partial seizures in refractory epilepsy patients and is rated as more “improved” than those receiving low stimulation in regards to overallhealth status.
Vagus nerve stimulation: effectiveness and tolerability in 64 paediatric patients with refractory epilepsies
- Medicine, PsychologyEpileptic disorders : international epilepsy journal with videotape
- 2011
VNS is an effective and well-tolerated treatment for paediatric patients with refractory epilepsies, improving quality of life and neuropsychological performance.