Vagus Nerve and Vagus Nerve Stimulation, a Comprehensive Review: Part II

@article{Yuan2016VagusNA,
  title={Vagus Nerve and Vagus Nerve Stimulation, a Comprehensive Review: Part II},
  author={Hsiangkuo Yuan and Stephen D. Silberstein},
  journal={Headache: The Journal of Head and Face Pain},
  year={2016},
  volume={56}
}
The development of vagus nerve stimulation (VNS) began in the 19th century. Although it did not work well initially, it introduced the idea that led to many VNS‐related animal studies for seizure control. In the 1990s, with the success of several early clinical trials, VNS was approved for the treatment of refractory epilepsy, and later for the refractory depression. To date, several novel electrical stimulating devices are being developed. New invasive devices are designed to automate the… Expand
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TLDR
Side effects of VNS increase with intensity of stimulation and can manifest throughout any branch of the vagus nerve, and although life-threatening events are rare, they require rapid recognition and immediate intervention. Expand
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TLDR
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TLDR
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TLDR
An overview of the diverse effects of VNS in the post-stroke condition, followed by a thorough discussion of the potential mechanisms responsible for its neuroprotective and neuroplasticity-enhancing properties, and the clinical applications of the recently emerging non-invasive VNS are outlined. Expand
Vagus Nerve Stimulation and the Cardiovascular System.
TLDR
The current state of preclinical and clinical studies, as well as the potential application of VNS in relation to the cardiovascular system are reviewed. Expand
A rodent model for long-term vagus nerve stimulation experiments
TLDR
A rodent model for longitudinal assessment of VNS is developed and validated with a long-term experiment incorporating continuous physiological monitoring in awake-behaving rats, showing easy-to-interface VNS system, electrode robustness and discernible physiological signals in aLong-term setup. Expand
Non-invasive vagus nerve stimulation for primary headache: A clinical update
TLDR
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