Vagus Nerve Prolonged Stimulation in Cats: Effects on Epileptogenesis (Amygdala Electrical Kindling): Behavioral and Electrographic Changes
@article{FernndezGuardiola1999VagusNP, title={Vagus Nerve Prolonged Stimulation in Cats: Effects on Epileptogenesis (Amygdala Electrical Kindling): Behavioral and Electrographic Changes}, author={Augusto Fern{\'a}ndez-Guardiola and A. Mart{\'i}nez and Alejandro Vald{\'e}s‐Cruz and V{\'i}ctor Manuel Magdaleno-Madrigal and D. Mart{\'i}nez and Rodrigo Fern{\'a}ndez-Mas}, journal={Epilepsia}, year={1999}, volume={40} }
Summary: Purpose: To analyze the effect of prolonged (daily) electrical vagus nerve stimulation (VNS) on daily amygdaloid kindling (AK) in freely moving cats.
92 Citations
The Effect of Vagus Nerve Stimulation on Epileptiform Activity Recorded from Hippocampal Depth Electrodes
- Biology, MedicineEpilepsia
- 2001
Clinical studies have established the efficacy of vagus nerve stimulation in patients with epilepsy, although the electrophysiologic effects of VNS on the human hippocampus and mesial temporal lobe structures remain unknown.
Effect of Electrical Stimulation of the Nucleus of the Solitary Tract on the Development of Electrical Amygdaloid Kindling in the Cat
- BiologyEpilepsia
- 2002
The effect of electrical stimulation of the nucleus of the solitary tract (NTS) on the development of electrical amygdaloid kindling (AK) in freely moving cats is analyzed.
Preemptive effect of nucleus of the solitary tract stimulation on amygdaloid kindling in freely moving cats
- Biology, PhysicsEpilepsia
- 2010
The aim of this study was to analyze the preemptive effect of NTS electrical stimulation on daily amygdaloid kindling (AK) in freely moving cats.
Brain Blood Flow Alterations Induced by Therapeutic Vagus Nerve Stimulation in Partial Epilepsy: I. Acute Effects at High and Low Levels of Stimulation
- BiologyEpilepsia
- 1998
Left cervical vagus nerve stimulation decreases complex partial seizures by unknown mechanisms of action and alters synaptic activities at vagal afferent terminations and in sites that receive polysynaptic projections from these medullary nuclei.
Vagus nerve stimulation.
- Medicine, BiologyNeurosurgical focus
- 2009
The goal of this work is to review the history of VNS and provide information on recent advances and applications of this technology.
Effect of vagus nerve stimulation on electrical kindling in different stages of seizure severity in freely moving cats
- Biology, PsychologyEpilepsy Research
- 2014
The Acute and Chronic Effect of Vagus Nerve Stimulation in Genetic Absence Epilepsy Rats from Strasbourg (GAERS)
- Psychology, BiologyEpilepsia
- 2005
This is a validated model for absence epilepsy, characterized by frequent spontaneous absences concomitant with spike and wave discharges on the EEG, which is conceptually important to investigate the efficacy of VNS in a controlled study by using this chronic epilepsy model.
Acute seizure-suppressing effect of vagus nerve stimulation in the amygdala kindled rat
- Biology, MedicineBrain Research
- 2010
Acute vagus nerve stimulation does not suppress spike and wave discharges in “Genetic Absence Epilepsy Rats from Strasbourg”
- BiologyEpilepsy Research
- 2004
THE EFFECTS OF VAGUS NERVE STIMULATION UPON EEG AS RECORDED FROM OCCIPITAL SUBDURAL ELECTRODES IN A HUMAN CASE
- Medicine
- 2000
The EEG background power spectra recorded from a left intracranial occipital contact were smaller with the VNS device “on” compared to when the device was “off” and VNS did not prevent or alter the course of electrographic seizures.
References
SHOWING 1-10 OF 51 REFERENCES
Repeated penicillin-induced amygdala epileptic focus in freely moving cats. EEG, polysomnographic (23-h recording), and brain mapping study
- Biology, PsychologyEpilepsy Research
- 1995
Effects of Sleep and Sleep Stage on Epileptic and Nonepileptic Seizures
- Psychology, MedicineEpilepsia
- 1997
It is shown that sleep increases the frequency, duration, and secondary generalization of seizures in patients with epilepsy and in animal models of epilepsy.
Amygdaloid kindling during rapid eye movement (REM) sleep in cats
- Biology, PsychologyNeuroscience Letters
- 1982
Generalized convulsive seizures induced by daily electrical stimulation of the amygdala in cats
- BiologyNeurology
- 1974
Seizure development was characterized by early distant propagation, amplitude growth of after-discharge, and development of interictal discharge along the ex-trapyramidal pathways through three distinct steps in which the mid-brain reticular formation plays a vital role in producing widespread secondary alteration and reorganization of brain function.
A permanent change in brain function resulting from daily electrical stimulation.
- Psychology, BiologyExperimental neurology
- 1969
Chronic Vagus Nerve Stimulation Increases the Latency of the Thalamocortical Somatosensory Evoked Potential
- Medicine, BiologyPacing and clinical electrophysiology : PACE
- 1992
The findings suggest that chronic vagus nerve stimulation does alter neuronal networks outside of the brain stem vagus system, and may potentially provide a means to clinically monitor and titrate this therapy.
Vagus Nerve Stimulation in Humans: Neurophysiological Studies and Electrophysiological Monitoring
- Medicine, BiologyEpilepsia
- 1990
Evidence from studies of experimental animals indicates that electrical stimulation of the vagus nerve alters behavioral and electrographic seizure activity and it is hoped that analysis of electrophysiological effects of vagal nerve stimulation will help elucidate which brain areas are affected.
The production of cobalt experimental epilepsy in the rat.
- BiologyElectroencephalography and clinical neurophysiology
- 1962
Anatomical, Physiological, and Theoretical Basis for the Antiepileptic Effect of Vagus Nerve Stimulation
- BiologyEpilepsia
- 1990
The vagus provides an easily accessible, peripheral route to modulate CNS function and is likely to relate to effects on the reticular activating system.