Vagovagal inhibition of motilin-induced phase III contractions by antral acidification in dog stomach.

@article{Yamamoto1994VagovagalIO,
  title={Vagovagal inhibition of motilin-induced phase III contractions by antral acidification in dog stomach.},
  author={O. Yamamoto and Yoichi Matsunaga and Norihiro Haga and Zen Itoh},
  journal={The American journal of physiology},
  year={1994},
  volume={267 1 Pt 1},
  pages={G129-34}
}
Gastric acidification at pH 1.0 strongly inhibits the spontaneously occurring and motilin-induced phase III contractions in canine and human stomach. In this study, we examined inhibition by gastric acidification in dogs following gastrojejunostomy, truncal vagotomy, and antrectomy. As a result, gastric acidification with 0.1 N HCl solution at pH 1.0 for 30 min at a rate of 1.0 ml/min significantly inhibited motilin-induced phase III activity to 23.5 +/- 5.9% of the control in the normal intact… CONTINUE READING