Vaginectomy and vaginoplasty for isolated vaginal recurrence 8 years after cervical cancer radical hysterectomy: A case report and literature review

@article{Lin2017VaginectomyAV,
  title={Vaginectomy and vaginoplasty for isolated vaginal recurrence 8 years after cervical cancer radical hysterectomy: A case report and literature review},
  author={Yanying Lin and Jingyi Zhou and Lin Dai and Yuan Cheng and Jianliu Wang},
  journal={Journal of Obstetrics and Gynaecology Research},
  year={2017},
  volume={43}
}
A subgroup of early‐stage cervical cancer patients suffer from vaginal cuff recurrence following a primary surgery; however, recurrence after a disease‐free interval of 5 years is rare. Treatments for isolated vaginal relapse remain controversial. Here we report a case of a 50‐year‐old woman with isolated vaginal cuff recurrence 8 years after primary radical surgery for cervical cancer. We conducted a vaginectomy and vaginoplasty using a type of tissue‐engineered biomaterial graft. Three… Expand
Cervical cancer remains a significant global health problem, particularly in developing countries, where cervical cancer is a leading cause of cancer-associated death in women (1). The risk factors for cervical cancer development primarily include human papillomavirus (HPV) infection (accounting for
Previous microrna (mir) microarray analysis revealed that mir-218 is downregulated in cervical cancer tissues. The present study aimed to further evaluate the expression of mir-218 in cervical cancerExpand
miR-218 functions as a tumor suppressor gene in cervical cancer
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The results revealed that miR-218 was downregulated in the tumor tissues and plasma of patients with cervical cancer, with expression associated with the advanced clinicopathological characteristics of patients, including HPV positivity, tumor size, blood vessel invasion and lymph node metastasis. Expand
miR-122 Inhibits the Cervical Cancer Development by Targeting the Oncogene RAD21.
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The data suggested that miR-122 could block malignant growth and promoted apoptosis by targeting RAD21 in CC and overexpression of RAD21 restored the roles of miR -122 in CC. Expand

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