Vaginal progesterone for preventing preterm birth and adverse perinatal outcomes in singleton gestations with a short cervix: a meta-analysis of individual patient data.

@article{Romero2017VaginalPF,
  title={Vaginal progesterone for preventing preterm birth and adverse perinatal outcomes in singleton gestations with a short cervix: a meta-analysis of individual patient data.},
  author={Roberto Romero and Agust{\'i}n Conde-Agudelo and Eduardo Borges da Fonseca and John M O'brien and Elcin Cetingoz and George W. Creasy and Sonia S. Hassan and Kypros H. Nicolaides},
  journal={American journal of obstetrics and gynecology},
  year={2017},
  volume={218 2},
  pages={
          161-180
        }
}
BACKGROUND The efficacy of vaginal progesterone for preventing preterm birth and adverse perinatal outcomes in singleton gestations with a short cervix has been questioned after publication of the OPPTIMUM study. OBJECTIVE To determine whether vaginal progesterone prevents preterm birth and improves perinatal outcomes in asymptomatic women with a singleton gestation and a midtrimester sonographic short cervix. STUDY DESIGN We searched MEDLINE, EMBASE, LILACS, and CINAHL (from their… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 164 REFERENCES

Interventions for women with mid-trimester short cervix: which ones work?

  • Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
  • 2017

The choice of progestogen for thepreventionofpretermbirth inwomen with singleton pregnancy and prior preterm birth

R Romero, KH Nicolaides, A Conde-Agudelo
  • Am J Obstet Gynecol
  • 2017