Vagally mediated gastric relaxation induced by intestinal nutrients in the dog.

  title={Vagally mediated gastric relaxation induced by intestinal nutrients in the dog.},
  author={Fernando Azpiroz and J. R. Malagelada},
  journal={The American journal of physiology},
  volume={251 6 Pt 1},
Using a gastric barostat to measure gastric tone, we previously demonstrated that nutrient perfusion into the intestine induces gastric relaxation. To investigate the pathway of this enterogastric reflex we surgically isolated the vagi either in a cervical skin tunnel (3 dogs) or within an implanted supradiaphragmatic cooling jacket (3 dogs). In the conscious fasted dogs, cervical or supradiaphragmatic vagal blockade by cooling (5 degrees C X 10 min) induced a reversible gastric relaxation… CONTINUE READING
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