Vagal control of sinoatrial rhythm: a mathematical model.

  title={Vagal control of sinoatrial rhythm: a mathematical model.},
  author={Socrates Dokos and Branko George Celler and Nigel H. Lovell},
  journal={Journal of theoretical biology},
  volume={182 1},
The ionic mechanisms underlying vagal control of the cardiac pacemaker were investigated using a new single cell mathematical model of sinoatrial node electrical activity. The model was formulated from a wide range of electrophysiological data available in the literature, with particular reference to whole cell recordings from enzymatically isolated sinoatrial node cells. Development of the model was prompted by the lack of an existing physiologically accurate formulation of sinoatrial node… CONTINUE READING
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