Vagal afferent modulation of a nociceptive reflex in rats: involvement of spinal opioid and monoamine receptors

@article{Ren1988VagalAM,
  title={Vagal afferent modulation of a nociceptive reflex in rats: involvement of spinal opioid and monoamine receptors},
  author={Ke Ren and Alan Randich and Gerald F. Gebhart},
  journal={Brain Research},
  year={1988},
  volume={446},
  pages={285-294}
}
Modulation of the spinal nociceptive tail flick (TF) reflex by electrical stimulation of subdiaphragmatic or cervical vagal afferent fibers was characterized in rats lightly anesthetized with pentobarbital. Cervical vagal afferent stimulation (VAS) inhibited the TF reflex in a pulse width-, frequency-, and intensity-dependent fashion. The optimum parameters for inhibition of the TF reflex were determined to be 2.0 ms pulse width, 20 Hz frequency with a threshold (T) current of 60 microA… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

Similar Papers

Loading similar papers…