Vagal afferent control of abdominal expiratory activity in response to hypoxia and hypercapnia in rats.

@article{Lemes2014VagalAC,
  title={Vagal afferent control of abdominal expiratory activity in response to hypoxia and hypercapnia in rats.},
  author={Eduardo V Lemes and Daniel Breseguello Zoccal},
  journal={Respiratory physiology & neurobiology},
  year={2014},
  volume={203},
  pages={90-7}
}
In the present study, we tested the hypothesis that vagal afferent information modulates the pattern of expiratory response to hypercapnia and hypoxia. Simultaneous recordings of airflow, diaphragmatic (DIA) and oblique abdominal muscle (ABD) activities were performed in anesthetized (urethane, 1.2g/kg), tracheostomized, spontaneously breathing male Wistar rats (290-320g, n=12). The animals were exposed to hypercapnia (7 and 10% CO2 for 5min) and hypoxia (7% O2 for 1min) before and after… CONTINUE READING
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