Vagal Paraganglia Bind Biotinylated Interleukin-1 Receptor Antagonist: A Possible Mechanism for Immune-to-Brain Communication

@article{Goehler1997VagalPB,
  title={Vagal Paraganglia Bind Biotinylated Interleukin-1 Receptor Antagonist: A Possible Mechanism for Immune-to-Brain Communication},
  author={Lisa E. Goehler and Jane K. Relton and David Dripps and Rachel Kiechle and N Tartaglia and Steven F. Maier and Linda R. Watkins},
  journal={Brain Research Bulletin},
  year={1997},
  volume={43},
  pages={357-364}
}
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281 Citations

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A novel mechanism by which IL-1β may serve as a molecular link between the immune system and vagus nerve, and thus the CNS is suggested.
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  • 2002
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The results imply that the carotid body not only serves as a chemoreceptor for modulation of cardiorespiratory performance, as traditionally recognized, but also acts as a cytokine chemorereceptor for sensing immune signals.
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