Vacuum‐Assisted Closure: A New Method for Wound Control and Treatment: Animal Studies and Basic Foundation
@article{Morykwas1997VacuumAssistedCA, title={Vacuum‐Assisted Closure: A New Method for Wound Control and Treatment: Animal Studies and Basic Foundation}, author={Michael J. Morykwas and Louis C. Argenta and Erica I. Shelton-Brown and Wyman T. McGuirt}, journal={Annals of Plastic Surgery}, year={1997}, volume={38}, pages={553–562} }
A series of basic animal studies using a new subatmospheric pressure technique (The V.A.C.) to expedite wound healing are presented. The technique entails placing an open-cell foam into the wound, sealing the site with an adhesive drape, and applying subatmospheric pressure (125 mmHg below ambient) that is transmitted to the wound in a controlled manner. Utilizing a pig model, four studies were undertaken to determine the effect of subatmospheric pressure on laser Doppler-measured blood flow in…
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