Vacuole membrane fusion

@article{Bayer2003VacuoleMF,
  title={Vacuole membrane fusion},
  author={Martin J. Bayer and Christoph Reese and Susanne B{\"u}hler and Christopher G. Peters and Andreas Mayer},
  journal={The Journal of Cell Biology},
  year={2003},
  volume={162},
  pages={211 - 222}
}
Pore models of membrane fusion postulate that cylinders of integral membrane proteins can initiate a fusion pore after conformational rearrangement of pore subunits. In the fusion of yeast vacuoles, V-ATPase V0 sectors, which contain a central cylinder of membrane integral proteolipid subunits, associate to form a transcomplex that might resemble an intermediate postulated in some pore models. We tested the role of V0 sectors in vacuole fusion. V0 functions in fusion and proton translocation… CONTINUE READING

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