Vacuolated oocytes: fertilization and embryonic arrest following intra-cytoplasmic sperm injection in a patient exhibiting persistent oocyte macro vacuolization—Case report

@article{Wallbutton2010VacuolatedOF,
  title={Vacuolated oocytes: fertilization and embryonic arrest following intra-cytoplasmic sperm injection in a patient exhibiting persistent oocyte macro vacuolization—Case report},
  author={Sarah Wallbutton and Jason Kasraie},
  journal={Journal of Assisted Reproduction and Genetics},
  year={2010},
  volume={27},
  pages={183-188}
}
To describe a case of homogeneous macro vacuolar formation in oocytes from a patient undergoing IVF/ICSI over 3 cycles and implications thereof. Case report and analysis of cycle outcomes including spindle visualization to determine severity of internal disruption caused. Characteristic macro vacuoles (>25 μm diameter) were identified in the vast majority of oocytes. Spindle visualization identified that macro vacuoles were not associated with spindle displacement. IVF resulted in failed… CONTINUE READING

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case report

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