Vaccinia virus evasion of regulated cell death.

  title={Vaccinia virus evasion of regulated cell death.},
  author={David L Veyer and Guia Carrara and Carlos Maluquer de Motes and Geoffrey L Smith},
  journal={Immunology letters},
Regulated cell death is a powerful anti-viral mechanism capable of aborting the virus replicative cycle and alerting neighbouring cells to the threat of infection. The biological importance of regulated cell death is illustrated by the rich repertoire of host signalling cascades causing cell death and by the multiple strategies exhibited by viruses to block death signal transduction and preserve cell viability. Vaccinia virus (VACV), a poxvirus and the vaccine used to eradicate smallpox… CONTINUE READING