Vaccinia virus L1 binds to cell surfaces and blocks virus entry independently of glycosaminoglycans.


L1 and A28 are vaccinia virus (VACV) envelope proteins which are essential for cellular entry. However, their specific roles during entry are unknown. We tested whether one or both of these proteins might serve as receptor binding proteins (RBP). We found that a soluble, truncated form of L1, but not A28, bound to cell surfaces independently of… (More)
DOI: 10.1016/j.virol.2008.12.019