Vaccines against polysaccharide antigens.

  title={Vaccines against polysaccharide antigens.},
  author={Gregory B. Lesinski and M. A. Julie Westerink},
  journal={Current drug targets. Infectious disorders},
  volume={1 3},
Encapsulated bacteria such as Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae serogroup B (Hib) are a major cause of disease worldwide. Vaccine development against these organisms has targeted their capsular polysaccharides (CPS), as anti-capsular antibodies often protect against disease. The capsular polysaccharide vaccines that have been available against these organisms are neither immunogenic nor protective in young children and certain immunocompromised… CONTINUE READING


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