Vaccine safety: current and future challenges.

@article{Chen1998VaccineSC,
  title={Vaccine safety: current and future challenges.},
  author={R. T. Chen and Beth F. Hibbs},
  journal={Pediatric annals},
  year={1998},
  volume={27 7},
  pages={
          445-55
        }
}
  • R. Chen, B. Hibbs
  • Published 1 July 1998
  • Medicine, Political Science, Biology
  • Pediatric annals
Immunizations are responsible for preventing death and disability from disease and are among the most cost-effective and widely used public health interventions. However, it is also recognized that no vaccine is perfectly safe or effective. Some people will experience side effects from vaccines, and a few may not experience a complete immunologic response to a vaccine, leaving them susceptible to disease. Sustaining high vaccine coverage rates may become more of a challenge as people question… 
Safety of Routine Childhood Vaccinations
TLDR
Effectively communicating this uncertainty and continuing to improve understanding of rare risks and risk factors are essential for “mature” immunisation programs to maintain public confidence in immunisations.
Vaccine refusal, mandatory immunization, and the risks of vaccine-preventable diseases.
TLDR
Although some clinicians have discontinued or have considered discontinuing their provider relationship with patients who refuse vaccines, the American Academy of Pediatrics Committee on Bioethics recommends that clinicians address vaccine refusal by respectfully listening to parental concerns and discussing the risks of nonvaccination.
Vaccine safety
Safety and Efficacy of the Common Vaccines against COVID-19
TLDR
RNA-based vaccines have a number of advantages and are one of the most promising vaccines identified to date and are particularly important during a pandemic, however, further improvements are required.
Controversies in immunization practices: vaccine safety and implications for midwifery practice.
  • B. Hackley
  • Medicine, Political Science
    Journal of midwifery & women's health
  • 2002
Public Health Policy and Vaccine-Preventable Disease: The Case for Immunization.
TLDR
It is the position that both the demonstrated and potential benefits of well-regulated vaccine programs far outweigh the potential health risks posed to the general public.
Epidemiology of vaccine hesitancy in the United States
Vaccines are among the most effective public health interventions against infectious diseases. However, there is evidence in the United States for parents either delaying or refusing recommended
Communicating the benefits and risks of vaccines.
TLDR
Physicians should be prepared to answer patients' or parents' questions about common as well as alleged vaccine-related adverse events and must utilize the Vaccine Information Statements for vaccines covered under the National Vaccine Injury Compensation Program.
Do Parents Understand Immunizations? A National Telephone Survey
TLDR
Although the majority of parents understand the benefits of immunization and support its use, many parents have important misconceptions that could erode their confidence in vaccines.
A Review of Traditional Vaccine-Preventable Diseases and the Potential Impact on the Otolaryngologist
TLDR
Vaccination and vaccine exemption rates continue to put the United States and many areas of the world at risk for outbreaks of vaccine-preventable diseases.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 53 REFERENCES
The complicated task of monitoring vaccine safety.
TLDR
A continual effort to monitor data effectively and to develop more precise ways of assessing risks of vaccines is necessary to ensure public confidence in immunization programs.
The Vaccine Adverse Event Reporting System (VAERS).
Vaccine Safety Datalink project: a new tool for improving vaccine safety monitoring in the United States. The Vaccine Safety Datalink Team.
TLDR
Preliminary design, data collection, and analytic capability of the Vaccine Safety Datalink project has been validated by replication of previous known associations between seizures and DTP and MMR vaccines.
A randomized comparison of reactogenicity and immunogenicity of two whole-cell pertussis vaccines.
TLDR
Although the Lederle product had substantially lower reactogenicity in this study than previously reported for that vaccine, the MPHBL vaccine was significantly less reactogenic in nearly all clinical categories.
Acellular Pertussis Vaccines
TLDR
The safety of DTaP vaccines has now been established in infants receiving inoculations at 2,4 and 6 months of age and in other 2 and 3 inoculation sequences below 1 year of age, as well as in toddlers, preschool children and in adults.
Epidemiology of pertussis in a developed country with low vaccination coverage: the Italian experience.
TLDR
Trends and characteristics of Italian children with pertussis are examined and the low vaccine coverage appears to be caused by the ambivalence of the Italian pediatric community about the vaccine rather than parental concerns about vaccine safety.
Immunization tracking systems: experience of the CDC Vaccine Safety Datalink sites.
TLDR
The effort required to establish Immunization Tracking Systems at each site is described, which can be a valuable means for assessing vaccine coverage, evaluating barriers to complete immunization, and studying the effectiveness of interventions design to improve immunization coverage.
Legal/ethical aspects of vaccinations.
  • W. Schumacher
  • Medicine, Political Science
    Developments in biological standardization
  • 1979
TLDR
Vaccinations have been and are a most successful instrument of preventive medicine and the readiness of the population to cooperate in vaccination campaigns depends very much on a clear solution of those questions.
...
1
2
3
4
5
...