Vaccine safety: Analysis of oral polio vaccine CHAT stocks

@article{Berry2001VaccineSA,
  title={Vaccine safety: Analysis of oral polio vaccine CHAT stocks},
  author={Neil J. Berry and Clare Davis and Adrian Jenkins and David J Wood and Philip D. Minor and Geoffrey C. Schild and M. Bottiger and Harvey Holmes and Neil M. Almond},
  journal={Nature},
  year={2001},
  volume={410},
  pages={1046-1047}
}
Batches of experimental oral vaccines against poliovirus (OPV CHAT) that were administered in Central Africa in the 1950s have been implicated in the origin of the AIDS pandemic because of possible retroviral contamination during the vaccine's manufacture, which allegedly involved chimpanzee kidney cells. Here we use a molecular analysis to show that two CHAT type-1 polio vaccine stocks were prepared from macaque and not chimpanzee cells, and contain neither human nor simian immunodeficiency… Expand
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