Vaccine protection of chickens against antigenically diverse H5 highly pathogenic avian influenza isolates with a live HVT vector vaccine expressing the influenza hemagglutinin gene derived from a clade 2.2 avian influenza virus.

@article{Kapczynski2015VaccinePO,
  title={Vaccine protection of chickens against antigenically diverse H5 highly pathogenic avian influenza isolates with a live HVT vector vaccine expressing the influenza hemagglutinin gene derived from a clade 2.2 avian influenza virus.},
  author={Darrell R. Kapczynski and Motoyuki Esaki and Kristi Moore Dorsey and Haijun Jiang and Mark W. Jackwood and Mauro Pires Moraes and Yannick Gardin},
  journal={Vaccine},
  year={2015},
  volume={33 9},
  pages={1197-205}
}
Vaccination is an important tool in the protection of poultry against avian influenza (AI). For field use, the overwhelming majority of AI vaccines produced are inactivated whole virus formulated into an oil emulsion. However, recombinant vectored vaccines are gaining use for their ability to induce protection against heterologous isolates and ability to overcome maternal antibody interference. In these studies, we compared protection of chickens provided by a turkey herpesvirus (HVT) vector… CONTINUE READING

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