Vaccine properties of antigens entrapped in microparticles produced by spray-drying technique and using various polyester polymers.

@article{Baras2000VaccinePO,
  title={Vaccine properties of antigens entrapped in microparticles produced by spray-drying technique and using various polyester polymers.},
  author={B Baras and M. A. Benoit and Odile Poulain-Godefroy and A M Schacht and Andr{\'e} Capron and Joshua Gillard and Gilles Riveau},
  journal={Vaccine},
  year={2000},
  volume={18 15},
  pages={1495-505}
}
The present study investigated the suitability of various microparticles produced by spray-drying technique to entrap and preserve the physiochemical and biological properties of an antigen. These microparticles were constituted either by poly(lactide) polymers characterized by various molecular weight or poly(lactide-co-glycolide) polymers. The recombinant 28 kDa glutathione S-transferase of Schistosoma mansoni (rSm28GST) characterized by major epitopes involved in the active site of this… CONTINUE READING