Vaccine-induced enhancement of viral infections.

  title={Vaccine-induced enhancement of viral infections.},
  author={Willem Huisman and Byron E. E. Martina and G F Rimmelzwaan and Rob A. Gruters and Albert D M E Osterhaus},
  volume={27 4},
Examples of vaccine-induced enhancement of susceptibility to virus infection or of aberrant viral pathogenesis have been documented for infections by members of different virus families. Several mechanisms, many of which still are poorly understood, are at the basis of this phenomenon. Vaccine development for lentivirus infections in general, and for HIV/AIDS in particular, has been little successful. Certain experimental lentiviral vaccines even proved to be counterproductive: they rendered… CONTINUE READING


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