Vaccine for contraception targeting sperm.

  title={Vaccine for contraception targeting sperm.},
  author={Rajesh K. Naz},
  journal={Immunological reviews},
Development of a vaccine(s) based on sperm antigens represents a promising approach to contraception. The utility of a sperm antigen in immunocontraception is contingent upon its tissue specificity, involvement in fertility and on raising high antibody titer, especially locally in the genital tract, that is capable of inducing reversible infertility. Several sperm antigens, such as lactate dehydrogenase C4, PH-20, sperm protein (SP)-10, fertilization antigen (FA)-1, FA-2, cleavage signal (CS)-1… CONTINUE READING
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