Vaccine entrapment in liposomes.

@article{Gregoriadis1999VaccineEI,
  title={Vaccine entrapment in liposomes.},
  author={Gregory Gregoriadis and Brenda McCormack and M Obrenovic and Roghieh Saffie and Brahim Zadi and Yvonne Perrie},
  journal={Methods},
  year={1999},
  volume={19 1},
  pages={
          156-62
        }
}
The use of liposomes as carriers of peptide, protein, and DNA vaccines requires simple, easy-to-scale-up technology capable of high-yield vaccine entrapment. Work from this laboratory has led to the development of techniques that can generate liposomes of various sizes, containing soluble antigens such as proteins and particulate antigens (e.g., killed or attenuated bacteria or viruses), as well as antigen-encoding DNA vaccines. Entrapment of vaccines is carried out by the dehydration… CONTINUE READING

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