Vaccine efficacy of recombinant GAPDH of Edwardsiella tarda against Edwardsiellosis.

  title={Vaccine efficacy of recombinant GAPDH of Edwardsiella tarda against Edwardsiellosis.},
  author={Ying Liu and Syun-ichirou Oshima and Kenrou Kurohara and Kouhei Ohnishi and Kenji Kawai},
  journal={Microbiology and immunology},
  volume={49 7},
Thirty-seven kilodalton glyceraldehyde-3-phosphate dehydrogenase (GAPDH) of Edwardsiella tarda was suggested to be an effective vaccine candidate against E. tarda infection in previous research. For developing a vaccine, obtaining GAPDH in large quantities is necessary. In this study, we determined the complete nucleotide sequence of the gene that encodes GAPDH of E. tarda, and overexpressed the GAPDH of E. tarda by using the Escherichia coli expression system. We immunized Japanese flounder… CONTINUE READING

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