Vaccine Safety and Efficacy Evaluation of a Recombinant Bovine Respiratory Syncytial Virus (BRSV) with Deletion of the SH Gene and Subunit Vaccines Based On Recombinant Human RSV Proteins: N-nanorings, P and M2-1, in Calves with Maternal Antibodies

@inproceedings{Blodrn2014VaccineSA,
  title={Vaccine Safety and Efficacy Evaluation of a Recombinant Bovine Respiratory Syncytial Virus (BRSV) with Deletion of the SH Gene and Subunit Vaccines Based On Recombinant Human RSV Proteins: N-nanorings, P and M2-1, in Calves with Maternal Antibodies},
  author={Krister Blod{\"o}rn and Sara H{\"a}gglund and Jenna Fix and Catherine Dubuquoy and Boby Makabi-Panzu and Michelle Thom and Per Karlsson and Jean-Louis Roque and Erika Karlstam and John Pringle and Jean-François {\'E}l{\'e}ou{\"e}t and Sabine Riffault and Geraldine Taylor and Jean-François Valarcher},
  booktitle={PloS one},
  year={2014}
}
The development of safe and effective vaccines against both bovine and human respiratory syncytial viruses (BRSV, HRSV) to be used in the presence of RSV-specific maternally-derived antibodies (MDA) remains a high priority in human and veterinary medicine. Herein, we present safety and efficacy results from a virulent BRSV challenge of calves with MDA, which were immunized with one of three vaccine candidates that allow serological differentiation of infected from vaccinated animals (DIVA): an… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 12 CITATIONS

RSV N-nanorings fused to palivizumab-targeted neutralizing epitope as a nanoparticle RSV vaccine.

  • Nanomedicine : nanotechnology, biology, and medicine
  • 2017
VIEW 2 EXCERPTS
CITES BACKGROUND

Non-invasive epicutaneous vaccine against Respiratory Syncytial Virus: Preclinical proof of concept.

  • Journal of controlled release : official journal of the Controlled Release Society
  • 2016
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 67 REFERENCES

Human and bovine respiratory syncytial virus vaccine research and development.

  • Comparative immunology, microbiology and infectious diseases
  • 2008
VIEW 20 EXCERPTS
HIGHLY INFLUENTIAL