Vaccination with virus-like particles containing H5 antigens from three H5N1 clades protects chickens from H5N1 and H5N8 influenza viruses.

Abstract

Highly pathogenic avian influenza (HPAI) viruses, especially H5N1 strains, represent a public health threat and cause widespread morbidity and mortality in domestic poultry. Recombinant virus-like particles (VLPs) represent a promising novel vaccine approach to control avian influenza including HPAI strains. Influenza VLPs contain viral hemagglutinin (HA… (More)
DOI: 10.1016/j.vaccine.2016.02.011

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Cite this paper

@article{Kapczynski2016VaccinationWV, title={Vaccination with virus-like particles containing H5 antigens from three H5N1 clades protects chickens from H5N1 and H5N8 influenza viruses.}, author={Darrell R. Kapczynski and Terrence M. Tumpey and Rachmat Hidajat and Aniko Zsak and Klaudia Chrzastek and Irina Tretyakova and Peter Pushko}, journal={Vaccine}, year={2016}, volume={34 13}, pages={1575-1581} }