Vaccination with recombinant paramyosin against the bovine lungworm Dictyocaulus viviparus considerably reduces worm burden and larvae shedding

@article{Strube2015VaccinationWR,
  title={Vaccination with recombinant paramyosin against the bovine lungworm Dictyocaulus viviparus considerably reduces worm burden and larvae shedding},
  author={Christina Strube and Claas Haake and Heinz Sager and Sandra Schorderet Weber and Ronald Kaminsky and Sandra Buschbaum and Deborah Elisabeth Joekel and Sabine Schicht and Elisabeth Kremmer and Julia Korrell and Thomas Schnieder and Georg von Samson-Himmelstjerna},
  journal={Parasites \& Vectors},
  year={2015},
  volume={8}
}
BackgroundThe lungworm Dictyocaulus viviparus, causing parasitic bronchitis in cattle, induces a temporary protective immunity that prevents clinical disease. A radiation-attenuated larvae based vaccine is commercially available in a few European countries, but has the disadvantages of a live vaccine. As a recombinant subunit vaccine would overcome these disadvantages, the parasite’s muscle protein paramyosin (PMY) was tested as a recombinant vaccine antigen.MethodsD. viviparus-PMY was… Expand
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