Vaccination with recombinant alphavirus or immune-stimulating complex antigen against respiratory syncytial virus.

@article{Chen2002VaccinationWR,
  title={Vaccination with recombinant alphavirus or immune-stimulating complex antigen against respiratory syncytial virus.},
  author={Margaret T Chen and Ke-fei Hu and Bj{\"o}rn Rozell and Claes Orvell and Bror Morein and Peter Liljestr{\"o}m},
  journal={Journal of immunology},
  year={2002},
  volume={169 6},
  pages={3208-16}
}
Respiratory syncytial virus (RSV) causes severe respiratory diseases in infants and young children. Inappropriate immunity to the virus can lead to disease enhancement upon subsequent infection. In this study, we have characterized the antiviral immunity elicited by the recombinant Semliki Forest virus (SFV) encoding the RSV fusion (F) and attachment (G) protein, and compared with that induced by the immune-stimulating complex (ISCOM)-incorporated FG proteins. Antiviral immunity against RSV… CONTINUE READING

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